2,451 research outputs found
X-Rays from the Nearby Solitary Millisecond Pulsar PSR J0030+0451 - the Final ROSAT Observations
We report on X-ray observations of the solitary 4.8 ms pulsar PSR J0030+0451.
The pulsar was one of the last targets observed in DEC-98 by the ROSAT PSPC.
X-ray pulses are detected on a level and make the source the
millisecond pulsar detected in the X-ray domain. The pulsed fraction
is found to be . The X-ray pulse profile is characterized by two
narrow peaks which match the gross pulse profile observed at 1.4 GHz. Assuming
a Crab-like spectrum the X-ray flux is in the range
erg s cm ( keV), implying an X-ray efficiency of
.Comment: Accepted for publication in Ap
Gravitational Waves Probe the Coalescence Rate of Massive Black Hole Binaries
We calculate the expected nHz--Hz gravitational wave (GW) spectrum from
coalescing Massive Black Hole (MBH) binaries resulting from mergers of their
host galaxies. We consider detection of this spectrum by precision pulsar
timing and a future Pulsar Timing Array. The spectrum depends on the merger
rate of massive galaxies, the demographics of MBHs at low and high redshift,
and the dynamics of MBH binaries. We apply recent theoretical and observational
work on all of these fronts. The spectrum has a characteristic strain
, just below the detection limit from
recent analysis of precision pulsar timing measurements. However, the amplitude
of the spectrum is still very uncertain owing to approximations in the
theoretical formulation of the model, to our lack of knowledge of the merger
rate and MBH population at high redshift, and to the dynamical problem of
removing enough angular momentum from the MBH binary to reach a GW-dominated
regime.Comment: 31 Pages, 8 Figures, small changes to match the published versio
Precision Timing Measurements of PSR J1012+5307
We present results and applications of high precision timing measurements of
the millisecond pulsar J1012+5307. Combining our radio observations with
results based on optical observations, we derive complete 3-D velocity
information for this system. Correcting for Doppler effects, we derive the
intrinsic spin parameters of this pulsar and a characteristic age of 8.6 +/-
1.9 Gyr. Our upper limit for the orbital eccentricity of only 8 * 10^-7 (68%
C.L.) is the smallest ever measured for a binary system. We demonstrate that
this makes the pulsar an ideal laboratory to test certain aspects of
alternative theories of gravitation. Our precise measurements suggest
deviations from a simple pulsar spin-down timing model, which are consistent
with timing noise and the extrapolation of the known behaviour of slowly
rotating pulsars.Comment: 9 pages, 6 figure
Radio-wave propagation through a medium containing electron-density fluctuations described by an anisotropic Goldreich-Sridhar spectrum
We study the propagation of radio waves through a medium possessing density
fluctuations that are elongated along the ambient magnetic field and described
by an anisotropic Goldreich-Sridhar power spectrum. We derive general formulas
for the wave phase structure function, visibility, angular broadening,
diffraction-pattern length scales, and scintillation time scale for arbitrary
distributions of turbulence along the line of sight, and specialize these
formulas to idealized cases.Comment: 25 pages, 3 figures, submitted to Ap
Vaccination against Foot-and-Mouth Disease : differentiating strategies and their epidemiological and economic consequences
The effectiveness of different control strategies against Foot-and-Mouth Disease (FMD) were investigated using epidemiological and economic models. A quick and large-scale vaccination within a radius of at least 2km is as effective as preemptive 1-km ring culling to mitigate FMD epidemics. Control measures should primarily target cattle farms. After the epidemic, most seropositive animals are expected on sheep farms and vaccinated cattle farms. An effective end-screening strategy should focus on these farms. Market acceptance by trade partners of products of vaccinated animals can limit the economic consequences of outbreaks of FMD.De effectiviteit van bestrijdingstrategieën tegen Mond-en-Klauwzeer (MKZ) is onderzochtmet behulp van epidemiologische en economische modellen. Het blijkt dat snelle en op grote schaal toegepaste vaccinatie in een straal van 2 km rond geïnfecteerde bedrijven net zo effectief is als ruimen in een straal van 1 km rond geïnfecteerde bedrijven bij het bestrijden van MKZ-uitbraken. Controlemaatregelen moeten vooral worden gericht op rundveebedrijven. Na de epidemie zijn de meeste seropositieve dieren te verwachten. De eindscreening zal zich op schapenbedrijven en gevaccineerde rundveebedrijven moeten richten. Acceptatie door internationale handelspartners van producten van gevaccineerde dieren kan de economische gevolgen van een uitbraak van MKZ beperken
Upper airway symptoms associate with the eosinophilic phenotype of COPD
Background: There is growing evidence that upper airway symptoms coexist with lower airway symptoms in COPD. Still, the prevalence and impact of upper airway disease on the nature and course of COPD remain unclear. We aimed to describe this in a cross-sectional study. //
Methods: We examined a cohort of COPD patients with pulmonary function tests, induced sputum, blood eosinophils, atopy tests and computed tomography (CT) of the paranasal sinuses. Lower airway symptoms were assessed using the COPD Assessment Test (CAT), and upper airway symptoms were assessed using the nasal subdomain of the 22-item Sino Nasal Outcome Test (SNOT22nasal). We recruited patients from five sites in Denmark and Sweden. We excluded patients with a history of asthma. //
Findings: In total, 180 patients (female 55%, age 67±8 years, forced expiratory volume in 1 s (FEV1 %) 52.4±16.6, Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage: A: 18%, B: 54%, C: 3%, D: 25%) were included in the study. Seventy-four patients (41%) reported high upper airway symptoms (UAS, defined as SNOT22nasal≥6) with a median score of 10 (IQR 8–13). Patients with high UAS reported higher CAT scores (17.4±7.5 versus 14.9±6.6, p<0.05) and displayed higher fractions of eosinophils in blood (median 3.0% (IQR 1.6–4.2%) versus 2.3% (IQR 1.4–3.1%), p<0.05) and in induced sputum (median 1.8% (IQR 0.3–7.1%) versus median 0.5% (IQR 0–1.7%), p<0.05). No differences in atopy, CT findings or exacerbation rates were observed. //
Conclusion: COPD patients with upper airway disease showed increased evidence of eosinophilic disease and increased lower airway symptom burden
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